Wednesday, September 26, 2012

Genetic Mutation


     According to a recent study, published by Sindya N. Bhanoo, the particular gene that produces the vivid dark stripes on cats is also liable for creating the spots on cheetahs. The reason for different spots being present is a predetermined mutation of the same gene resulting in cat stripes as well as spots on the cheetah to become ‘blotchy’. Dr. Stephen O’Brien, a geneticist at the University of St. Petersburg, Russia, as well as one of the lead researchers of the latest study noted that: “Nobody had any idea what the genes were that were involved in these things” (O’Brien). He also commented that when the feline genome became available, his team assembled to search for the unknown genes. This intriguing gene discovery, also known as: “Taqpep” is published in the current issue of the ‘Journal Science’. Dr. O’Brien and his colleagues findings were analyzed and found to be conclusive at the Hudson Alpha Institute for Biotechnology, in Alabama; the Frederick National Laboratory for Cancer Research, in Maryland; and Stanford University. Wondering why the gene is called “Taqpep?” This is a specific mutation of a gene found in cheetahs, belonging to a rare breed: known as the ‘king cheetah’ native to South Africa. ‘Tabbies’, which Dr. O’Brien clarified, with the mutation are more common in Europe where as ‘striped tabbies’ are more common in the United States. Dr. O’Brien ended on a note that, “we’re still fishing around to really unravel the pathways involved in pattern forming and pigmentation” (O’Brien).

* Information obtained at www.nytimes.com
* Pictures obtained at www.caitbiology.wikispaces.com & www.nytimes.com

 Figure 7.1













Figure 7.2 












(The "mackerel tabby" pattern (upper) and the "blotched tabby" pattern (lower).

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